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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
21.52
Human Site:
S508
Identified Species:
39.44
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
S508
G
S
T
S
M
I
F
S
T
G
P
Y
S
T
N
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
S519
G
S
T
S
M
I
F
S
T
G
P
Y
S
T
N
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
S785
G
S
T
S
M
I
F
S
T
G
P
Y
S
T
N
Dog
Lupus familis
XP_546939
1411
154543
A499
I
L
K
S
M
E
F
A
P
S
E
G
T
G
T
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
S506
G
S
T
S
T
I
F
S
T
G
P
Y
S
T
N
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
F555
L
V
F
P
S
P
F
F
T
A
K
G
P
L
L
Chicken
Gallus gallus
XP_425393
1673
183755
S653
G
S
T
S
M
I
F
S
T
G
P
Y
S
T
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
S460
A
A
K
A
A
L
L
S
A
N
H
S
A
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
A794
Q
E
D
S
N
G
L
A
A
V
A
M
A
A
H
Honey Bee
Apis mellifera
XP_623857
1936
209316
S750
S
S
T
T
A
L
T
S
P
P
S
F
Q
P
P
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
E395
K
N
R
R
L
Q
N
E
N
A
S
L
R
V
A
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
P532
H
T
P
E
P
P
Q
P
P
K
T
P
P
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
20
N.A.
93.3
0
N.A.
13.3
100
N.A.
6.6
N.A.
6.6
20
0
0
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
0
N.A.
13.3
100
N.A.
40
N.A.
26.6
40
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
16
0
0
16
16
16
8
0
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
8
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
54
8
0
0
0
8
0
0
0
% F
% Gly:
39
0
0
0
0
8
0
0
0
39
0
16
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
8
0
0
0
0
39
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
16
0
0
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
8
8
0
0
8
16
16
0
0
0
0
8
0
8
8
% L
% Met:
0
0
0
0
39
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
8
0
8
0
8
8
0
0
0
8
39
% N
% Pro:
0
0
8
8
8
16
0
8
24
8
39
8
16
8
8
% P
% Gln:
8
0
0
0
0
8
8
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
47
0
54
8
0
0
54
0
8
16
8
39
8
0
% S
% Thr:
0
8
47
8
8
0
8
0
47
0
8
0
8
39
16
% T
% Val:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _